How Does Wegovy® Work? | Wegovy® (semaglutide) Injection 2.4 mg (2024)

Scroll to Indication

Wegovy® may cause serious side effects, including:

  • Possible thyroid tumors, including cancer. Tell your healthcare provider if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In studies with rodents, Wegovy® and medicines that work like Wegovy® caused thyroid tumors, including thyroid cancer. It is not known if Wegovy® will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people
  • Do not use Wegovy® if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
  • you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
  • you have had a serious allergic reaction to semaglutide or any of the ingredients in Wegovy®
  • have or have had problems with your pancreas or kidneys
  • have type 2 diabetes and a history of diabetic retinopathy
  • have or have had depression, suicidal thoughts, or mental health issues
  • are pregnant or plan to become pregnant. Wegovy® may harm your unborn baby. You should stop using Wegovy® 2 months before you plan to become pregnant
  • are breastfeeding or plan to breastfeed. It is not known if Wegovy® passes into your breast milk

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Wegovy® may affect the way some medicines work and some medicines may affect the way Wegovy® works. Tell your healthcare provider if you are taking other medicines to treat diabetes, including sulfonylureas or insulin.

Wegovy® slows stomach emptying and can affect medicines that need to pass through the stomach quickly.

Wegovy® may cause serious side effects, including:

  • inflammation of your pancreas (pancreatitis). Stop using Wegovy® and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting. You may feel the pain from your abdomen to your back
  • gallbladder problems. Wegovy® may cause gallbladder problems, including gallstones. Some gallstones may need surgery. Call your healthcare provider if you have symptoms, such as pain in your upper stomach (abdomen), fever, yellowing of the skin or eyes (jaundice), or clay- colored stools
  • increased risk of low blood sugar (hypoglycemia), especially those who also take medicines for diabetes such as insulin or sulfonylureas. This can be a serious side effect. Talk to your healthcare provider about how to recognize and treat low blood sugar and check your blood sugar before you start and while you take Wegovy®. Signs and symptoms of low blood sugar may include dizziness or light-headedness, blurred vision, anxiety, irritability or mood changes, sweating, slurred speech, hunger, confusion or drowsiness, shakiness, weakness, headache, fast heartbeat, or feeling jittery
  • kidney problems (kidney failure). In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems to get worse. It is important for you to drink fluids to help reduce your chance of dehydration
  • serious allergic reactions. Stop using Wegovy® and get medical help right away, if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat
  • change in vision in people with type 2 diabetes. Tell your healthcare provider if you have changes in vision during treatment with Wegovy®
  • increased heart rate. Wegovy® can increase your heart rate while you are at rest. Tell your healthcare provider if you feel your heart racing or pounding in your chest and it lasts for several minutes
  • depression or thoughts of suicide. You should pay attention to any mental changes, especially sudden changes in your mood, behaviors, thoughts, or feelings. Call your healthcare provider right away if you have any mental changes that are new, worse, or worry you

The most common side effects of Wegovy® may include: nausea, diarrhea, vomiting, constipation, stomach (abdomen) pain, headache, tiredness (fatigue), upset stomach, dizziness, feeling bloated, belching, low blood sugar in people with type 2 diabetes, gas, stomach flu, heartburn, and runny nose or sore throat.

Please see Prescribing Information and Medication Guide for Wegovy®.

Wegovy® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

This site is intended for US patients only.

Scroll to ISI

WEGOVY® (semaglutide) injection 2.4 mg is an injectable prescription medicine used with a reduced calorie diet and increased physical activity:

  • to reduce the risk of major cardiovascular events such as death, heart attack, or stroke in adults with known heart disease and with either obesity or overweight.
  • that may help adults and children aged 12 years and older with obesity, or some adults with overweight who also have weight-related medical problems, to help them lose excess body weight and keep the weight off.

Wegovy® contains semaglutide and should not be used with other semaglutide-containing products or other GLP-1 receptor agonist medicines.

It is not known if Wegovy® is safe and effective for use in children under 12 years of age.

Scroll to Indication

Wegovy® may cause serious side effects, including:

  • Possible thyroid tumors, including cancer. Tell your healthcare provider if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In studies with rodents, Wegovy® and medicines that work like Wegovy® caused thyroid tumors, including thyroid cancer. It is not known if Wegovy® will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people
  • Do not use Wegovy® if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
  • you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
  • you have had a serious allergic reaction to semaglutide or any of the ingredients in Wegovy®
  • have or have had problems with your pancreas or kidneys
  • have type 2 diabetes and a history of diabetic retinopathy
  • have or have had depression, suicidal thoughts, or mental health issues
  • are pregnant or plan to become pregnant. Wegovy® may harm your unborn baby. You should stop using Wegovy® 2 months before you plan to become pregnant
  • are breastfeeding or plan to breastfeed. It is not known if Wegovy® passes into your breast milk

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Wegovy® may affect the way some medicines work and some medicines may affect the way Wegovy® works. Tell your healthcare provider if you are taking other medicines to treat diabetes, including sulfonylureas or insulin.

Wegovy® slows stomach emptying and can affect medicines that need to pass through the stomach quickly.

Wegovy® may cause serious side effects, including:

  • inflammation of your pancreas (pancreatitis). Stop using Wegovy® and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting. You may feel the pain from your abdomen to your back
  • gallbladder problems. Wegovy® may cause gallbladder problems, including gallstones. Some gallstones may need surgery. Call your healthcare provider if you have symptoms, such as pain in your upper stomach (abdomen), fever, yellowing of the skin or eyes (jaundice), or clay- colored stools
  • increased risk of low blood sugar (hypoglycemia), especially those who also take medicines for diabetes such as insulin or sulfonylureas. This can be a serious side effect. Talk to your healthcare provider about how to recognize and treat low blood sugar and check your blood sugar before you start and while you take Wegovy®. Signs and symptoms of low blood sugar may include dizziness or light-headedness, blurred vision, anxiety, irritability or mood changes, sweating, slurred speech, hunger, confusion or drowsiness, shakiness, weakness, headache, fast heartbeat, or feeling jittery
  • kidney problems (kidney failure). In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems to get worse. It is important for you to drink fluids to help reduce your chance of dehydration
  • serious allergic reactions. Stop using Wegovy® and get medical help right away, if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat
  • change in vision in people with type 2 diabetes. Tell your healthcare provider if you have changes in vision during treatment with Wegovy®
  • increased heart rate. Wegovy® can increase your heart rate while you are at rest. Tell your healthcare provider if you feel your heart racing or pounding in your chest and it lasts for several minutes
  • depression or thoughts of suicide. You should pay attention to any mental changes, especially sudden changes in your mood, behaviors, thoughts, or feelings. Call your healthcare provider right away if you have any mental changes that are new, worse, or worry you

The most common side effects of Wegovy® may include: nausea, diarrhea, vomiting, constipation, stomach (abdomen) pain, headache, tiredness (fatigue), upset stomach, dizziness, feeling bloated, belching, low blood sugar in people with type 2 diabetes, gas, stomach flu, heartburn, and runny nose or sore throat.

Scroll to ISI

WEGOVY® (semaglutide) injection 2.4 mg is an injectable prescription medicine used with a reduced calorie diet and increased physical activity:

  • to reduce the risk of major cardiovascular events such as death, heart attack, or stroke in adults with known heart disease and with either obesity or overweight.
  • that may help adults and children aged 12 years and older with obesity, or some adults with overweight who also have weight-related medical problems, to help them lose excess body weight and keep the weight off.

Wegovy® contains semaglutide and should not be used with other semaglutide-containing products or other GLP-1 receptor agonist medicines.

It is not known if Wegovy® is safe and effective for use in children under 12 years of age.

Please see Prescribing Information and Medication Guide for Wegovy®.

Wegovy® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

This site is intended for US patients only.

How Does Wegovy® Work? | Wegovy® (semaglutide) Injection 2.4 mg (2024)

FAQs

How Does Wegovy® Work? | Wegovy® (semaglutide) Injection 2.4 mg? ›

Wegovy® (semaglutide) Injection 2.4 mg. Your brain gets signals from different places in your body. Some of these signals are called appetite hormones that help regulate how much food you eat. Wegovy® works similarly to one of these natural appetite hormones, so you eat fewer calories and lose weight.

Do you lose weight on 2.4 Wegovy? ›

In clinical trials, most people taking 1.7-mg and 2.4-mg doses of Wegovy had lost 5% to 15% of their body weight after 68 weeks of treatment. In a small 2022 study , people with overweight or obesity had lost 5.9% of overall body weight after 3 months of using semaglutide.

Can you lose weight on semaglutide 2.4 mg? ›

The study found that a 6‐month use of semaglutide 2.4 mg resulted in a 10% decrease in weight and a reduction of 10.5 kg in adult participants with overweight/obesity.

How does the Wegovy shot work? ›

How does it work? Wegovy acts on areas of the brain which are involved in regulating your appetite. It increases feelings of fullness, reduces feelings of hunger and reduces the preference for high-fat foods. It also reduces blood sugar by promoting the release of insulin when blood sugar levels are high.

How do I know if I injected Wegovy correctly? ›

A few signs of a correctly administered injection include feeling little to no discomfort while injecting, no leakage of medication back out of the skin, and minimal blood or fluid at the injection site.

How long does it take to lose 20 lbs on Wegovy? ›

If you weigh 232 lbs at the start of Wegovy treatment, you can expect to lose 20 lbs in around 16-20 weeks (4-5 months). Again, noticeable weight loss on Wegovy occurs when you combine it with other weight loss efforts, such as a low-calorie diet and increased exercise.

How to maximize weight loss on Wegovy? ›

Health experts say there are several research-backed strategies that may help improve weight loss results while taking GLP-1 drugs. These include getting regular exercise, reducing stress, eating a healthy diet, and prioritizing sleep.

Can I start semaglutide at 2.4 mg? ›

The starting dose is 0.25 mg once a week, and you will gradually increase your dose every four weeks. Your health care provider can select either 1.7 mg or 2.4 mg for your maintenance dose.

How to speed up weight loss on semaglutide? ›

So now you know what to expect on your semaglutide weight loss journey, here are some handy tips to help you maximize your weight loss results.
  1. Eat little and often. ...
  2. Relish every bite. ...
  3. Make nourishing choices. ...
  4. Drink plenty of water. ...
  5. Lower your alcohol intake. ...
  6. Take it steady. ...
  7. Be active. ...
  8. Rotate injection sites.

What is the dark side of semaglutide? ›

Pancreatitis (swelling of the pancreas) may occur while you are using this medicine. Check with your doctor right away if you have sudden and severe stomach pain, chills, constipation, nausea, vomiting, fever, or lightheadedness.

How do you feel after first shot of Wegovy? ›

Key takeaways

Expect to feel normal on your first day taking Wegovy since the side effects don't start immediately. The most common side effects of Wegovy start a few days after the injection and include nausea, gastrointestinal discomfort, and decreased appetite.

Does Wegovy shrink your stomach? ›

Will Ozempic or Wegovy reduce belly fat? The answer appears to be yes. That Novo Nordisk-funded study of almost 2,000 overweight or obese adults without diabetes also found their visceral fat — the type that accumulates in the belly — was reduced from baseline with semaglutide, along with their total fat mass.

How quickly do people see results on Wegovy? ›

If you started Wegovy recently, it's important to understand that it can take some time to see results. Some people don't start seeing significant results for up to 20 weeks, possibly longer. Most people see their peak results by the one-year mark.

Where is the best spot to inject Wegovy? ›

It's approved for use in adults and children ages 12 and older. It can also lower the risk of serious cardiovascular problems in certain adults with heart disease. Wegovy is injected once a week under the skin of the stomach, upper thigh, or upper arm. Of these three areas, there's no “best” place to inject Wegovy.

Do higher doses of Wegovy work better? ›

If you stay on 0.25mg, you may not achieve maximal weight loss potential. An average of 15% weight loss over 68 weeks was only shown in patients who moved up the dosing schedule to reach a maintenance dose of 2.4mg. Weight loss effects will be most noticeable when you reach 2.4mg.

What is the number one side effect of Wegovy? ›

The most common side effects of Wegovy® may include:

Upset stomach. Dizziness. Feeling bloated. Belching.

What is the use of Wegovy 2.4 mg? ›

Weight-Loss Prescription Medication. Wegovy® (semaglutide) Injection 2.4 mg. For adults with obesity or some adults with overweight and weight-related medical problems, along with a reduced calorie diet and increased physical activity.

Can you lose weight on .25 semaglutide? ›

The short answer is that many of our patients lose weight in the first week of taking semaglutide. The first dose is small (0.25 mg). It is primarily used to gently introduce the medication to the body without risking developing severe side effects.

Can I lose 20 pounds in a month with semaglutide? ›

So with each higher dose, we should continue to see more and more weight loss. Remember that this is the average weight loss. We did have patients who lost a moderate amount but we also had patients losing over 15 pounds and even over 20 pounds in the first month!

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